Annual report pursuant to Section 13 and 15(d)

Income Taxes - Components of Deferred Income Tax Assets (Detail)

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Income Taxes - Components of Deferred Income Tax Assets (Detail) (USD $)
In Thousands, unless otherwise specified
Dec. 31, 2012
Dec. 31, 2011
Deferred tax assets:    
Deferred tax assets, Net operating loss carryforwards $ 8,216 $ 6,155
Deferred tax assets, Research and development credits 9,088 8,077
Deferred tax assets, Accrued expenses and other 1,970 644
Deferred tax assets, Stock-based compensation 3,184 1,685
Deferred tax assets, Gross 22,458 16,561
Less valuation allowance (22,243) (16,029)
Deferred tax assets, net 215 532
Deferred tax liability:    
Deferred tax liability, Depreciation and amortization (215) (532)
Net deferred tax assets